Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.47 |
| ▸ | FNTB | P49356 | 12/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152940 | 0.89 | FNTA (0.48) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL8541422 | 0.89 | ALDH1A1 (0.53) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL8520839 | 0.87 | ALDH1A1 (0.46) | FNTAFNTBALDH1A1LMNA | |
| SCHEMBL7483971 | 0.87 | FNTA (0.47) | FNTAFNTBALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL7482278 | 0.86 | FNTA (0.47) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL8522108 | 0.83 | FNTA (0.49) | FNTAFNTBALDH1A1LMNAMEN1 | |
| SCHEMBL3500676 | 0.83 | FNTA (0.60) | FNTAFNTBMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL8452831 | 0.79 | FNTA (0.55) | FNTAFNTBMEN1KMT2A | |
| SCHEMBL7749701 | 0.78 | SLC6A4 (0.65) | — | |
| SCHEMBL7483881 | 0.77 | FNTA (0.38) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000508335-A | — | — | 2000-07-04 | — | — | JP | claimed |
| EP-0934270-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1997045412-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-12-04 | — | — | WO | claimed |