Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 11/20 | 0.45 |
| ▸ | FNTB | P49356 | 11/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152940 | 0.89 | FNTA (0.48) | ALDH1A1LMNAFNTAFNTB | |
| SCHEMBL8153147 | 0.87 | FNTA (0.47) | ALDH1A1LMNAFNTAFNTB | |
| SCHEMBL8541422 | 0.86 | ALDH1A1 (0.53) | ALDH1A1LMNAFNTAFNTB | |
| SCHEMBL7483971 | 0.86 | FNTA (0.47) | ALDH1A1LMNAFNTAFNTB | |
| Hydrochloric Acid SCHEMBL7482278 | 0.85 | FNTA (0.47) | ALDH1A1LMNAFNTAFNTB | |
| SCHEMBL3499735 | 0.84 | FNTA (0.58) | ALDH1A1LMNAFNTAFNTBTACR1 | |
| Trifluoroacetic Acid SCHEMBL8452331 | 0.82 | FNTA (0.56) | FNTAFNTBTACR1DRD4 | |
| SCHEMBL8522108 | 0.81 | FNTA (0.49) | ALDH1A1LMNAFNTAFNTB | |
| SCHEMBL7483881 | 0.76 | FNTA (0.38) | FNTAFNTBDRD4 | |
| Hydrochloric Acid SCHEMBL7748868 | 0.76 | FNTA (0.38) | FNTAFNTBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952842-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-11-03 | — | — | EP | disclosed |
| WO-1997038664-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | disclosed |