Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.71 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146021 | 0.94 | MTNR1A (0.68) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8146661 | 0.93 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8152799 | 0.89 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8136431 | 0.84 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8134992 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8150330 | 0.83 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8152291 | 0.82 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8137636 | 0.81 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8137814 | 0.80 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8140872 | 0.77 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737685-B1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-07-19 | — | — | EP | disclosed |
| EP-0737685-A1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-10-16 | — | — | EP | disclosed |