Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490659 | 0.82 | TDP1 (0.40) | TDP1ERN1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL1312079 | 0.78 | CYP3A4 (0.50) | TDP1ERN1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL11330008 | 0.78 | ERN1 (0.39) | TDP1ERN1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL14127223 | 0.77 | ALDH1A1 (0.37) | TDP1ERN1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL6100984 | 0.74 | ERN1 (0.54) | TDP1ERN1ALDH1A1MEN1MAPT | |
| SCHEMBL9712522 | 0.73 | CYP3A4 (0.40) | TDP1ERN1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL4168460 | 0.73 | TDP1 (0.45) | TDP1ERN1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL4808231 | 0.73 | ERN1 (0.57) | TDP1ERN1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL6601947 | 0.73 | ERN1 (0.58) | TDP1ERN1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL27290171 | 0.73 | ERN1 (0.52) | TDP1ERN1CYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630914-B1 | Ethylene/propylene copolymer rubbers | UNION CARBIDE CHEM PLASTIC (US) | 2000-06-07 | — | — | EP | disclosed |