Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871992 | 0.78 | — | — | |
| SCHEMBL4753189 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8158152 | 0.72 | PKN1 (0.33) | ALDH1A1 | |
| SCHEMBL13318356 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL13871989 | 0.66 | — | — | |
| SCHEMBL1004793 | 0.66 | HRH4 (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL12844664 | 0.65 | — | — | |
| SCHEMBL22016185 | 0.64 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8159293 | 0.63 | — | — | |
| SCHEMBL1392811 | 0.62 | HRH4 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902252-B2 | Inhibitors of D-amino acid oxidase | SEPRACOR, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2008089453-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2008-07-24 | — | — | WO | disclosed |