Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150936 | 0.95 | NPC1 (0.50) | HTTTDP1SMN1; SMN2LMNANPC1 | |
| SCHEMBL9952390 | 0.89 | POLB (0.58) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL9952394 | 0.89 | POLB (0.58) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL2224525 | 0.88 | POLB (0.57) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL12516446 | 0.88 | POLB (0.57) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL2223306 | 0.88 | POLB (0.57) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL12517246 | 0.88 | POLB (0.57) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL2224519 | 0.88 | POLB (0.57) | HTTTDP1POLBAPEX1SMN1; SMN2 | |
| SCHEMBL7458090 | 0.88 | LMNA (0.64) | TDP1SMN1; SMN2LMNAAPPRAB9A | |
| SCHEMBL7458093 | 0.88 | LMNA (0.64) | TDP1SMN1; SMN2LMNAAPPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |