Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL8201543 | 0.84 | CA5A (0.42) | CA5ACA5BALDH1A1CYP1A2CYP2D6 | |
| Tert-Butylamine SCHEMBL1401394 | 0.80 | — | — | |
| Nitric Acid SCHEMBL3187096 | 0.77 | CA5A (0.53) | CA5ACA5BALDH1A1 | |
| Nitric Acid SCHEMBL10579135 | 0.77 | — | — | |
| Methyl Alcohol SCHEMBL27508368 | 0.76 | ALDH1A1 (0.35) | ALDH1A1 | |
| Nitric Acid SCHEMBL8192719 | 0.76 | CA5A (0.44) | CA5ACA5BALDH1A1 | |
| Nitric Acid SCHEMBL8201551 | 0.74 | CA5A (0.42) | CA5ACA5BALDH1A1 | |
| Nitric Acid SCHEMBL4635145 | 0.74 | CA5A (0.42) | CA5ACA5BCYP1A2CYP2D6 | |
| Isopropylamine SCHEMBL8341815 | 0.74 | — | — | |
| Nitric Acid SCHEMBL4114469 | 0.73 | CA5A (0.67) | CA5ACA5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7658872-B2 | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS, INC. (US) | 2010-02-09 | — | — | US | claimed |
| US-20050103705-A1 | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS, INC. | 2005-05-19 | — | — | US | claimed |
| EP-1483033-A4 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | OSMONICS INC (US) | 2005-04-13 | — | — | EP | claimed |
| EP-1483033-A1 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | OSMONICS, INC. (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003074152-A1 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | GE OSMONICS, INC. (US) | 2003-09-12 | — | — | WO | claimed |
| US-9314743-B2 | Residential reverse osmosis system | PENTAIR RESIDENTIAL FILTRATION, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-8262910-B2 | Residential reverse osmosis system | G.E. Osmonics—Pentair Joint Venture (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110309011-A1 | RESIDENTIAL REVERSE OSMOSIS SYSTEM | GE OSMONICS, INC. (US) | 2011-12-22 | — | — | US | disclosed |
| US-8052865-B2 | Residential reverse osmosis system | GE OSMONICS, INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-20110073535-A1 | RESIDENTIAL REVERSE OSMOSIS SYSTEM | GE OSMONICS, INC. (US) | 2011-03-31 | — | — | US | disclosed |
| US-7862710-B2 | Residential reverse osmosis system | GE OSMONICS, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-7828970-B2 | Residential reverse osmosis system | GE OSMONICS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| CN-1646203-A | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS INC (US) | 2005-07-27 | — | — | CN | disclosed |
| EP-1539334-A1 | RESIDENTIAL REVERSE OSMOSIS SYSTEM | GE Osmonics, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050103705-A1 | Process for preparing semipermeable membranes having improved permeability | GE OSMONICS, INC. | 2005-05-19 | — | — | US | disclosed |
| EP-1483033-A4 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | OSMONICS INC (US) | 2005-04-13 | — | — | EP | disclosed |
| EP-1483033-A1 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | OSMONICS, INC. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2004014528-A9 | RESIDENTIAL REVERSE OSMOSIS SYSTEM | GE OSMONICS INC (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2004014528-A1 | RESIDENTIAL REVERSE OSMOSIS SYSTEM | GE OSMONICS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2003074152-A1 | A PROCESS FOR PREPARING SEMIPERMEABLE MEMBRANES HAVING IMPROVED PERMEABILITY | GE OSMONICS, INC. (US) | 2003-09-12 | — | — | WO | disclosed |