Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153356 | 1.00 | TDP1 (0.50) | TDP1PTGS2ALDH1A1MAPK1MAPT | |
| SCHEMBL1174503 | 0.86 | MAPT (0.64) | TDP1PTGS2ALDH1A1MAPK1MAPT | |
| SCHEMBL3602553 | 0.86 | MAPT (0.64) | TDP1PTGS2ALDH1A1MAPK1MAPT | |
| SCHEMBL989659 | 0.86 | MAPT (0.64) | TDP1PTGS2ALDH1A1MAPK1MAPT | |
| SCHEMBL9657741 | 0.84 | BACE1 (0.57) | PTGS2MAPTLMNABACE1MAOB | |
| SCHEMBL4933000 | 0.84 | PTGS2 (0.54) | TDP1PTGS2ALDH1A1MAPK1MAPT | |
| SCHEMBL4933003 | 0.84 | PTGS2 (0.54) | TDP1PTGS2ALDH1A1MAPK1MAPT | |
| SCHEMBL9657746 | 0.84 | BACE1 (0.57) | PTGS2MAPTLMNABACE1MAOB | |
| SCHEMBL4861773 | 0.83 | PTGS2 (0.52) | PTGS2ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL22398056 | 0.83 | ALDH1A1 (0.51) | TDP1PTGS2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |