Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.55 |
| ▸ | MMP1 | P03956 | 5/20 | 0.53 |
| ▸ | MMP3 | P08254 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | MMP7 | P09237 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153443 | 1.00 | FKBP1A (0.55) | FKBP1AMMP1MMP3MMP13MMP7 | |
| SCHEMBL7385275 | 1.00 | FKBP1A (0.55) | FKBP1AMMP1MMP3MMP13MMP7 | |
| SCHEMBL7387818 | 0.93 | MMP1 (0.60) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7386603 | 0.90 | MMP1 (0.63) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7378813 | 0.90 | MMP1 (0.63) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7386604 | 0.90 | MMP1 (0.63) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7378815 | 0.90 | MMP1 (0.63) | MMP1MMP3MMP13MMP7MMP9 | |
| SCHEMBL7390454 | 0.88 | MMP1 (0.56) | FKBP1AMMP1MMP3MMP13MMP7 | |
| SCHEMBL7389960 | 0.87 | MMP1 (0.57) | FKBP1AMMP1MMP3MMP13MMP7 | |
| SCHEMBL7419864 | 0.86 | FKBP1A (0.53) | FKBP1AMMP1MMP3MMP13MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107291-A | ANTIINFLAMMATORY AGENT | AMGEN INC. (US) | 2000-08-22 | — | — | US | disclosed |