Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 10/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154589 | 0.87 | PTGER1 (0.45) | PTGER1CYP1A2LMNACCR5ALDH1A1 | |
| SCHEMBL8168635 | 0.82 | PTGER1 (0.48) | PTGER1CYP1A2LMNACCR5ALDH1A1 | |
| SCHEMBL7671498 | 0.82 | LMNA (0.41) | PTGER1CYP1A2LMNAALDH1A1CYP3A4 | |
| SCHEMBL7667879 | 0.80 | SMN1; SMN2 (0.40) | PTGER1CYP1A2LMNAALDH1A1CYP3A4 | |
| SCHEMBL8155916 | 0.78 | PTGER1 (0.49) | PTGER1CYP1A2LMNACCR5ALDH1A1 | |
| SCHEMBL4868816 | 0.78 | PTGER1 (0.54) | PTGER1CYP1A2CCR5USP28USP25 | |
| SCHEMBL9055421 | 0.78 | PTGER1 (0.46) | PTGER1CYP1A2LMNACCR5ALDH1A1 | |
| SCHEMBL7666981 | 0.77 | ALDH1A1 (0.39) | PTGER1CYP1A2LMNAALDH1A1CYP3A4 | |
| SCHEMBL7803947 | 0.77 | PTGER1 (0.48) | PTGER1CYP1A2LMNACCR5ALDH1A1 | |
| SCHEMBL7816449 | 0.77 | ATM (0.36) | PTGER1CYP1A2LMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773930-B1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LTD (GB) | 2000-10-11 | — | — | EP | disclosed |
| EP-0773930-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003380-A1 | AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS | ZENECA LIMITED (GB) | 1996-02-08 | — | — | WO | disclosed |