Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216527 | 0.98 | DGKA (0.50) | DGKALMNAPAMKDM4EDUSP3 | |
| SCHEMBL9400193 | 0.98 | DGKA (0.50) | DGKALMNAPAMKDM4EDUSP3 | |
| SCHEMBL8945612 | 0.98 | DGKA (0.50) | DGKALMNAPAMKDM4EDUSP3 | |
| SCHEMBL8945727 | 0.98 | DGKA (0.50) | DGKALMNAPAMKDM4EDUSP3 | |
| SCHEMBL9095803 | 0.94 | ALDH1A1 (0.41) | DGKALMNAPAMKDM4EDUSP3 | |
| SCHEMBL733968 | 0.86 | ALDH1A1 (0.46) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL7155025 | 0.82 | DGKA (0.52) | DGKALMNAPAMMEN1KMT2A | |
| SCHEMBL28837891 | 0.82 | DGKA (0.52) | DGKALMNAPAMMEN1KMT2A | |
| SCHEMBL7439608 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL7891158 | 0.80 | DGKA (0.55) | DGKALMNAPAMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000189187-A | PRODUCTION OF OPTICALLY ACTIVE 1,1,1-TRIFLUORO-2-ALKANOL | CHISSO CORP | 2000-07-11 | — | — | JP | disclosed |