Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | S100A4 | P26447 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 3/20 | 0.41 |
| ▸ | TDP2 | O95551 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CDC25A | P30304 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | GALK1 | P51570 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128020 | 0.81 | S100A4 (0.53) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL30673380 | 0.81 | S100A4 (0.53) | MEN1KMT2AMAPTS100A4MAPK1 | |
| Acetone SCHEMBL29195741 | 0.76 | MEN1 (0.48) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL31121517 | 0.73 | CDC25B (0.44) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL13649360 | 0.71 | S100A4 (0.50) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL15765912 | 0.70 | MEN1 (0.50) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL9709418 | 0.69 | PTPN1 (0.54) | MEN1KMT2AMAPTS100A4MAPK1 | |
| Anthraquinone SCHEMBL616605 | 0.69 | MEN1 (0.71) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL5810776 | 0.69 | PARK7 (0.58) | MEN1KMT2AMAPTS100A4MAPK1 | |
| SCHEMBL29715761 | 0.68 | STAT3 (0.58) | MEN1KMT2AMAPTMAPK1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008495-A2 | ANTIPROLIFERATIVE NAPHTHOQUINONES, DERIVATIVES, COMPOSITIONS, AND USES THEREOF | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2000-02-17 | — | — | WO | disclosed |