Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.43 |
| ▸ | RXRG | P48443 | 10/20 | 0.43 |
| ▸ | RXRB | P28702 | 9/20 | 0.43 |
| ▸ | RARG | P13631 | 6/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145948 | 0.85 | RXRA (0.60) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8146556 | 0.81 | RXRA (0.68) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8159678 | 0.81 | RXRA (0.68) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8153962 | 0.81 | RXRA (0.68) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8851049 | 0.81 | RXRA (0.68) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8850282 | 0.81 | RXRA (0.68) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8154604 | 0.74 | RXRA (0.50) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8159338 | 0.73 | TP53 (0.37) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8159340 | 0.73 | TP53 (0.37) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8153500 | 0.73 | RXRA (0.71) | RXRARXRGRXRBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800503-B1 | NOVEL TRIENOIC RETINOID COMPOUNDS AND METHODS | LIGAND PHARM INC (US) | 2000-05-10 | — | — | EP | claimed |