SCHEMBL8154699

SCHEMBL8154699

CC1=C(C)C(C)(C)C([Ti](C(=O)c2ccccc2)(C(=O)c2ccccc2)C(=O)c2ccccc2)=C1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.35
CES1 P23141 5/20 0.35
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
DAO P14920 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925424 0.78 TSHR (0.42) KMT2ANPSR1TSHRALDH1A1NPC1
SCHEMBL7927401 0.76 TSHR (0.41) KMT2ANPSR1TSHRALDH1A1NPC1
SCHEMBL7930330 0.75 TSHR (0.40) KMT2ANPSR1TSHRALDH1A1NPC1
SCHEMBL7919505 0.75 TSHR (0.40) KMT2ANPSR1TSHRALDH1A1NPC1
SCHEMBL7925018 0.68 KCNN4 (0.46) CES1KMT2ANPSR1L3MBTL1MAPT
Benzoic Acid SCHEMBL7764207 0.68 TSHR (0.48) CES2CES1KMT2ATSHRALDH1A1
Benzoic Acid SCHEMBL6066250 0.68 TSHR (0.48) CES2CES1KMT2ATSHRALDH1A1
SCHEMBL7930746 0.67
Benzoic Acid SCHEMBL653417 0.66 CA2 (0.50) CES2CES1KMT2ANPSR1TSHR
Benzoic Acid SCHEMBL7764204 0.66 CA2 (0.50) CES2CES1KMT2ANPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6100352-A USING A CATALYST CONSISTING OF A TRANSITION METAL COMPOUND, A COMPOUND CAPABLE OF FORMING AN IONIC COMPOUND BY REACTING WITH THE TRANSITION METAL COMPOUND OR AN OXYGEN-CONTAINING COMPOUND SUCH AS ALUMINOXANE IDEMITSU KOSAN CO., LTD. (JP) 2000-08-08 US disclosed
EP-0810238-B1 A process for producing polymer IDEMITSU KOSAN CO (JP) 2000-02-02 EP disclosed
EP-0810238-A1 A process for producing polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-12-03 EP disclosed