Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 4/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7764204 | 0.81 | CA2 (0.50) | CA2CA4NPC1TP53GAA | |
| Benzoic Acid SCHEMBL25441 | 0.74 | CA2 (0.89) | CA2CA4HPGDSMN1; SMN2CES2 | |
| Benzoic Acid SCHEMBL11789341 | 0.72 | CA2 (0.94) | CA2CA4HPGDSMN1; SMN2CES2 | |
| Benzoic Acid SCHEMBL28337190 | 0.70 | CA2 (0.80) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL27345977 | 0.70 | CA2 (0.90) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL11740323 | 0.70 | CA2 (0.80) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL158696 | 0.70 | CA2 (0.80) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL1445056 | 0.70 | CA2 (0.89) | CA2CA4HPGDSMN1; SMN2CES2 | |
| Benzoic Acid SCHEMBL4525348 | 0.70 | CA2 (0.89) | CA2CA4HPGDSMN1; SMN2CES2 | |
| Benzoic Acid SCHEMBL457494 | 0.70 | CA2 (0.89) | CA2CA4HPGDSMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982236-B2 | Process to polymerize olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2006-01-03 | — | — | US | claimed |
| US-20040039138-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2004-02-26 | — | — | US | claimed |
| US-6656866-B2 | Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts | UNIVATION TECHNOLOGIES, LLC | 2003-12-02 | — | — | US | claimed |
| US-20030207762-A9 | CATALYST PREPARATION METHOD | UNIVATION TECHNOLOGIES, LLC | 2003-11-06 | — | — | US | claimed |
| EP-1358216-A2 | START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS | Univation Technologies LLC (US) | 2003-11-05 | — | — | EP | claimed |
| US-6620894-B2 | Calibration; using coordination catalyst | UNIVATION TECHNOLOGIES, LLC | 2003-09-16 | — | — | US | claimed |
| EP-0961784-B1 | IMPROVED CONTROL OF SOLUTION CATALYST DROPLET SIZE WITH AN EFFERVESCENT SPRAY NOZZLE | UNION CARBIDE CHEM PLASTIC (US) | 2002-10-23 | — | — | EP | claimed |
| US-20020132937-A1 | Start-up procedure for multiple catalyst polymerization systems | UNIVATION TECHNOLOGIES, LLC | 2002-09-19 | — | — | US | claimed |
| US-20020119890-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2002-08-29 | — | — | US | claimed |
| WO-2002050127-A2 | START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-27 | — | — | WO | claimed |
| US-5962606-A | VAPOR PHASE POLYMERIZING OF AN ALPHA-OLEFIN USING LIQUID CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-10-05 | — | — | US | claimed |
| EP-3105261-B9 | PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY | UNIVATION TECH LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| EP-4223802-A2 | POLYMERIZATION CATALYST | Univation Technologies, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-2953985-B1 | PREPARATION OF POLYOLEFIN | UNIVATION TECH LLC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3105261-B1 | PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY | UNIVATION TECH LLC (US) | 2022-10-12 | — | — | EP | disclosed |
| US-5693727-A | INTRODUCING MONOMERS INTO POLYMERIZATION ZONE CONTAINING BED OF GROWING POLYMER PARTICLES, INTRODUCING UNSUPPORTED POLYMERIZATION CATALYST IN LIQUID FORM INTO VESSEL, WITHDRAWING POLYMERIC PRODUCT, UNREACTED MONOMERS, GASES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0784062-A2 | Process for production of long-chain branched polyolefins | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0770629-A2 | A process for preparing an in situ polyethylene blend | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0735057-A1 | Catalysts for the production of polyolefins | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5527752-A | ZIRCONIUM OR HAFNIUM COMPLEXES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |