Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377091 | 1.00 | KMT2A (0.78) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL8146978 | 0.93 | KMT2A (0.82) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL13697478 | 0.90 | KMT2A (0.78) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL7384067 | 0.85 | ALDH1A1 (0.74) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL2253820 | 0.83 | ALDH1A1 (0.75) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL1366897 | 0.81 | KDM4E (0.77) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL30232368 | 0.80 | ALDH1A1 (1.00) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL29425001 | 0.80 | ALDH1A1 (1.00) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL194445 | 0.80 | ALDH1A1 (1.00) | KMT2AMEN1RAB9APOLBHDAC3 | |
| SCHEMBL8146977 | 0.80 | GABRA1 (0.78) | KMT2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132454-A1 | CARBOLINES AND THEIR USE AS IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2008-11-06 | — | — | WO | disclosed |