SCHEMBL8155100

SCHEMBL8155100

CO[SiH](c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.44
TDP1 Q9NUW8 3/20 0.44
LMNA P02545 2/20 0.36
ALDH1A1 P00352 3/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
RELA Q04206 1/20 0.34
CHRNA7 P36544 1/20 0.33
TSHR P16473 4/20 0.32
CYP3A4 P08684 1/20 0.32
TEAD4 Q15561 1/20 0.32
AGXT P21549 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482552 0.91 ACHE (0.43) ACHETDP1LMNAALDH1A1SMN1; SMN2
SCHEMBL3299815 0.80 ACHE (0.47) ACHETDP1LMNAALDH1A1CA1
SCHEMBL1703269 0.78 ACHE (0.44) ACHETDP1LMNAALDH1A1CA1
SCHEMBL4105504 0.76 ACHE (0.42) ACHETDP1LMNAALDH1A1CA1
SCHEMBL9284526 0.76 ACHE (0.42) ACHETDP1LMNAALDH1A1CA1
SCHEMBL675766 0.74 CA4 (0.41) ACHELMNAALDH1A1CA1CA2
SCHEMBL3871927 0.74 ACHE (0.40) ACHETDP1LMNAALDH1A1CA1
P-Xylene SCHEMBL28289203 0.73 ACHE (0.53) ACHETDP1LMNAALDH1A1CA1
SCHEMBL3875561 0.72 ACHE (0.38) ACHETDP1LMNAALDH1A1CA1
SCHEMBL3294404 0.72 ACHE (0.46) ACHETDP1LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426853-B2 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI CHEMICALS INC (JP) 2000-03-29 EP disclosed
EP-0469153-B1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL IND (JP) 1996-04-10 EP disclosed
US-5300581-A Melting and kneading mixture of polymer particles, graft modifier and radical initiator MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 US disclosed
US-5292811-A Crystalline propylene polymer, amorphous ethylene-alpha-olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0469153-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-02-05 EP disclosed
EP-0426853-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
EP-0409992-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-30 EP disclosed