Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.39 |
| ▸ | FNTB | P49356 | 7/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8141557 | 0.99 | FNTA (0.39) | FNTAFNTBCYP19A1 | |
| SCHEMBL8034890 | 0.89 | FNTA (0.47) | FNTAFNTBCYP19A1 | |
| SCHEMBL8154511 | 0.89 | FNTA (0.47) | FNTAFNTBCYP19A1 | |
| Hydrochloric Acid SCHEMBL8147142 | 0.89 | FNTA (0.46) | FNTAFNTBCYP19A1 | |
| SCHEMBL8147164 | 0.88 | FNTA (0.38) | FNTAFNTB | |
| SCHEMBL3501299 | 0.84 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL3685883 | 0.84 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL3684995 | 0.84 | FNTA (0.56) | FNTAFNTB | |
| Hydrochloric Acid SCHEMBL9082057 | 0.84 | FNTA (0.55) | FNTAFNTB | |
| SCHEMBL3500218 | 0.79 | FNTA (0.53) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060038-A | Radiolabeled farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0981728-A2 | RADIOLABELED FARNESYL-PROTEIN TRANSFERASE INHIBITORS | Merck & Co., Inc. (US) | 2000-03-01 | — | — | EP | disclosed |
| WO-1999000654-A2 | RADIOLABELED FARNESYL-PROTEIN TRANSFERASE INHIBITORS | MERCK & CO., INC. (US) | 1999-01-07 | — | — | WO | disclosed |