Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GPR183 | P32249 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141116 | 0.89 | ALDH1A1 (0.60) | LMNANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8147041 | 0.88 | NPC1 (0.65) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8139756 | 0.88 | GAA (0.60) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL8155116 | 0.85 | MAPT (0.56) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL8153503 | 0.84 | GPR183 (0.53) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8141166 | 0.84 | GPR183 (0.53) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8146931 | 0.84 | HPGD (0.52) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8154799 | 0.83 | ALDH1A1 (0.57) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8153641 | 0.83 | KDM4E (0.41) | MAPTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL8148327 | 0.82 | HRH3 (0.51) | MAPTLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |