SCHEMBL8153641

SCHEMBL8153641

C=CC(=O)OC1CCN(C(=O)/C=C/c2ccc(C)cc2C)CC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ENPP2 Q13822 5/20 0.40
MAPT P10636 3/20 0.40
ITGAL P20701 2/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153364 0.87 KDM4E (0.40) KDM4EENPP2MAPTLMNAHPGD
SCHEMBL8155182 0.83 MAPT (0.59) KDM4EMAPTLMNAHPGDNPC1
SCHEMBL8148362 0.79 KDM4E (0.57) KDM4EMAPTITGALLMNAHPGD
SCHEMBL8148437 0.79 ITGAL (0.47) ENPP2MAPTITGALLMNARAB9A
SCHEMBL8146027 0.78 KDM4E (0.44) KDM4EENPP2MAPTITGALLMNA
SCHEMBL8153628 0.76 KMT2A (0.60) KDM4EMAPTITGALLMNAHPGD
SCHEMBL8154832 0.75 POLB (0.49) MAPTITGALLMNASMN1; SMN2
SCHEMBL8141116 0.75 ALDH1A1 (0.60) LMNAHPGDNPC1RAB9AGAA
SCHEMBL8147041 0.74 NPC1 (0.65) MAPTNPC1RAB9ASMN1; SMN2GAA
SCHEMBL8148914 0.74 ALDH1A1 (0.50) KDM4EMAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed