Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
| ▸ | RXRA | P19793 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155194 | 1.00 | PPARG (0.52) | PPARGRXRAHTR6MAOBMIF | |
| SCHEMBL8154646 | 0.88 | RXRA (0.44) | PPARGRXRAMAOBMEN1MAPT | |
| SCHEMBL8154649 | 0.88 | RXRA (0.44) | PPARGRXRAMAOBMEN1MAPT | |
| SCHEMBL8148098 | 0.85 | CYP1A2 (0.51) | PPARGRXRAMEN1ALDH1A1MAPT | |
| SCHEMBL8148095 | 0.85 | CYP1A2 (0.51) | PPARGRXRAMEN1ALDH1A1MAPT | |
| SCHEMBL7147839 | 0.84 | PPARG (0.72) | PPARGRXRAMEN1ALDH1A1MAPT | |
| SCHEMBL8150043 | 0.84 | PPARG (0.72) | PPARGRXRAMEN1ALDH1A1MAPT | |
| SCHEMBL8150041 | 0.84 | PPARG (0.72) | PPARGRXRAMEN1ALDH1A1MAPT | |
| SCHEMBL8154671 | 0.83 | CYP1A2 (0.53) | PPARGRXRAHTR6MAPT | |
| SCHEMBL8154670 | 0.83 | CYP1A2 (0.53) | PPARGRXRAHTR6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028116-A | Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia | CELL PATHWAYS, INC. (US) | 2000-02-22 | — | — | US | disclosed |