Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154646 | 1.00 | RXRA (0.44) | RXRAPPARGLCKPTGS1MEN1 | |
| SCHEMBL8155194 | 0.88 | PPARG (0.52) | RXRAPPARGMEN1KMT2AMAPT | |
| SCHEMBL8155195 | 0.88 | PPARG (0.52) | RXRAPPARGMEN1KMT2AMAPT | |
| SCHEMBL8148098 | 0.86 | CYP1A2 (0.51) | RXRAPPARGLCKPTGS1MEN1 | |
| SCHEMBL8148095 | 0.86 | CYP1A2 (0.51) | RXRAPPARGLCKPTGS1MEN1 | |
| SCHEMBL8430723 | 0.86 | RXRA (0.43) | RXRAPPARGLCKMEN1KMT2A | |
| SCHEMBL8154670 | 0.84 | CYP1A2 (0.53) | RXRAPPARGLCKPTGS1MAPT | |
| SCHEMBL8154671 | 0.84 | CYP1A2 (0.53) | RXRAPPARGLCKPTGS1MAPT | |
| SCHEMBL8154789 | 0.83 | RXRA (0.64) | RXRAPPARGPTGS1MEN1KMT2A | |
| SCHEMBL8154792 | 0.83 | RXRA (0.64) | RXRAPPARGPTGS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028116-A | Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia | CELL PATHWAYS, INC. (US) | 2000-02-22 | — | — | US | disclosed |