Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151297 | 0.81 | OPRL1 (0.46) | OPRL1EPHX2EPHX1LTA4HMAPT | |
| SCHEMBL8138756 | 0.81 | OPRL1 (0.46) | OPRL1EPHX2EPHX1LTA4HMAPT | |
| SCHEMBL8147635 | 0.79 | SLC18A3 (0.35) | KDM4ETHRBATML3MBTL1CHRM2 | |
| SCHEMBL27923823 | 0.78 | L3MBTL1 (0.42) | EPHX1KDM4EL3MBTL1CHRM2CHRM5 | |
| SCHEMBL8149867 | 0.78 | OPRL1 (0.44) | OPRL1EPHX2EPHX1LTA4HMAPT | |
| SCHEMBL8138855 | 0.77 | EPHX2 (0.46) | OPRL1EPHX2EPHX1LTA4HMAPT | |
| SCHEMBL13798632 | 0.77 | EPHX2 (0.46) | OPRL1EPHX2EPHX1LTA4HMAPT | |
| SCHEMBL12750502 | 0.77 | EPHX2 (0.46) | OPRL1EPHX2EPHX1LTA4HMAPT | |
| SCHEMBL23640028 | 0.76 | EPHX2 (0.46) | OPRL1EPHX2EPHX1MAPTKDM4E | |
| SCHEMBL27528187 | 0.76 | HRH3 (0.41) | MAPTKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |