Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150190 | 1.00 | DGAT1 (0.47) | DGAT1NCEH1DHODHMAPTKDM4E | |
| SCHEMBL8150396 | 0.82 | NNMT (0.40) | DGAT1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL428805 | 0.80 | DGAT1 (0.60) | DGAT1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1788262 | 0.80 | DGAT1 (0.55) | DGAT1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL31200433 | 0.80 | DGAT1 (0.55) | DGAT1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL8140936 | 0.80 | IRAK4 (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8153971 | 0.79 | LCK (0.41) | DGAT1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8141517 | 0.79 | KDM4E (0.50) | MAPTKDM4EALDH1A1LCKCYP2A6 | |
| SCHEMBL8149236 | 0.79 | KDM4E (0.50) | MAPTKDM4EALDH1A1LCKCYP2A6 | |
| SCHEMBL8150193 | 0.79 | LCK (0.41) | DGAT1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |