O-Xylene

O-Xylene

SCHEMBL8155397

COC(C)=O.Cc1ccccc1C

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TSHR P16473 4/20 0.53
ACHE P22303 1/20 0.53
HPGD P15428 4/20 0.52
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 2/20 0.45
GAA P10253 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 1/20 0.44
EPHX1 P07099 1/20 0.42
POLB P06746 1/20 0.42
PTPN1 P18031 1/20 0.42
KCNN4 O15554 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL8993576 0.84 ALDH1A1 (0.53) ALDH1A1TSHRACHEHPGDSMN1; SMN2
O-Xylene SCHEMBL29141440 0.84 TSHR (0.53) ALDH1A1TSHRACHEHPGDSMN1; SMN2
O-Xylene SCHEMBL510350 0.83 TSHR (0.67) ALDH1A1TSHRACHEHPGDSMN1; SMN2
O-Xylene SCHEMBL28230316 0.83 TSHR (0.67) ALDH1A1TSHRACHEHPGDSMN1; SMN2
Toluene SCHEMBL34952 0.82 LMNA (0.55) ALDH1A1TSHRACHESMN1; SMN2NPC1
Naphthalene SCHEMBL1961577 0.81 ALDH1A1 (0.56) ALDH1A1TSHRHPGDNPC1RAB9A
O-Xylene SCHEMBL8506142 0.80 TSHR (0.62) ALDH1A1TSHRACHEHPGDSMN1; SMN2
O-Xylene SCHEMBL7156831 0.80 TSHR (0.62) ALDH1A1TSHRACHEHPGDSMN1; SMN2
O-Xylene SCHEMBL1723905 0.80 TSHR (0.62) ALDH1A1TSHRACHEHPGDSMN1; SMN2
O-Xylene SCHEMBL11417240 0.80 TSHR (0.62) ALDH1A1TSHRACHEHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105572714-B Scintillator panel and radiation detector 柯尼卡美能达株式会社 2018-11-30 CN disclosed
CN-105549062-B Scintillator panel, radiation detector and their manufacturing method 柯尼卡美能达株式会社 2018-08-24 CN disclosed
CN-104240786-B Radiographic image conversion panel 柯尼卡美能达株式会社 2017-04-12 CN disclosed
CN-103415498-A Benzylidene substituted 2,4-pentanedione compounds and use thereof as stabilizers SYTHEON LTD 2013-11-27 CN disclosed
CN-103402963-A Compositions and methods for stabilizing ingredients using 2, 4-pentanedione compounds SYTHEON LTD 2013-11-20 CN disclosed
CN-103159676-A Compounds and application thereof LU ZHONGLIN 2013-06-19 CN disclosed
CN-101312752-B Novel absorbent product SCA HYGIENE PROD AB 2012-09-05 CN disclosed
CN-102014865-A Cosmetics comprising cistus plant extracts EVONIK GOLDSCHMIDT GMBH 2011-04-13 CN disclosed
CN-101312752-A Novel absorbent product SCA HYGIENE PROD AB (SE) 2008-11-26 CN disclosed
JP-2000086516-A USE OF TERFENADINECARBOXYLATE SEPRACOR INC 2000-03-28 JP disclosed