Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977466 | 0.92 | NPC1 (0.69) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| Benzoic Acid SCHEMBL11551976 | 0.90 | NPC1 (0.68) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL9359752 | 0.87 | NPC1 (0.50) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL9359760 | 0.87 | NPC1 (0.50) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL11234092 | 0.87 | MAPT (0.54) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL5708171 | 0.87 | NPC1 (0.63) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL5708166 | 0.87 | NPC1 (0.63) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL19690361 | 0.87 | NPC1 (0.67) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL231011 | 0.87 | NPC1 (0.67) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL29924607 | 0.87 | NPC1 (0.67) | NPC1RAB9AHPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813515-B1 | Process for the preparation of esters of stilbenedicarbonic acid and process for the preparation of p-(chloromethyl)-benzoic acid | EASTMAN CHEM CO (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0813516-B1 | PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS | EASTMAN CHEM CO (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0813516-A1 | PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS | EASTMAN CHEMICAL COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027578-A1 | PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS | EASTMAN CHEMICAL COMPANY (US) | 1996-09-12 | — | — | WO | disclosed |
| US-5473098-A | Process for the preparation of stilbenedicarboxylate esters | EASTMAN CHEMICAL COMPANY (US) | 1995-12-05 | — | — | US | disclosed |
| US-5470998-A | Process for the preparation of esters of stilbenedicarboxylic acid | EASTMAN CHEMICAL COMPANY (US) | 1995-11-28 | — | — | US | disclosed |