Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359760 | 1.00 | NPC1 (0.50) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL5708085 | 0.89 | NPC1 (0.56) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL5708093 | 0.89 | NPC1 (0.56) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL8155474 | 0.87 | NPC1 (0.60) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL5708075 | 0.85 | NPC1 (0.63) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL16363763 | 0.85 | NPC1 (0.63) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL11234092 | 0.83 | MAPT (0.54) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL11765490 | 0.82 | MAPT (0.57) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL20370085 | 0.81 | NPC1 (0.59) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11779586 | 0.81 | MAPT (0.56) | NPC1MAPTRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385890-B1 | Pocess for the preparation of stilbene derivatives | EASTMAN CHEM CO (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0472525-A1 | PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990010001-A1 | PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |
| US-4921964-A | Process for the preparation of stilbene derivatives | EASTMAN KODAK COMPANY (US) | 1990-05-01 | — | — | US | disclosed |