Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932807 | 0.82 | SLC22A6 (0.35) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL3788751 | 0.82 | GPR84 (0.36) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL9472210 | 0.82 | SLC22A6 (0.35) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL28956447 | 0.80 | ALDH1A1 (0.39) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL21520585 | 0.80 | CACNA2D1 (0.41) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL16877098 | 0.80 | CACNA2D1 (0.36) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL10777880 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6828027 | 0.78 | CACNA2D1 (0.39) | SLC22A6CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL2015252 | 0.78 | GPR84 (0.42) | SLC22A6TDP1 | |
| SCHEMBL28521529 | 0.78 | GPR84 (0.42) | SLC22A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |