Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612425 | 0.92 | MMP1 (0.56) | MMP1 | |
| SCHEMBL7503750 | 0.86 | MMP1 (0.42) | MMP1CTSKCTSLCTSSMMP2 | |
| SCHEMBL8157744 | 0.83 | MMP1 (0.47) | MMP1CTSKCTSLCTSSMMP2 | |
| SCHEMBL8155901 | 0.82 | MMP1 (0.69) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL7612394 | 0.79 | MMP1 (0.55) | MMP1 | |
| SCHEMBL8150256 | 0.75 | MMP1 (0.58) | MMP1 | |
| SCHEMBL7612399 | 0.73 | MMP1 (0.82) | MMP1 | |
| SCHEMBL7548061 | 0.69 | MMP1 (0.68) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL7503743 | 0.69 | MMP1 (0.62) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL8458038 | 0.68 | MMP1 (0.68) | MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147061-A | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS; ORAL DISEASES | PFIZER INC. (US) | 2000-11-14 | — | — | US | disclosed |