Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150256 | 0.91 | MMP1 (0.58) | MMP1RAB9ANPC1 | |
| SCHEMBL8155905 | 0.83 | MMP1 (0.46) | MMP1CTSLCTSSCTSKMMP2 | |
| SCHEMBL8157742 | 0.83 | MMP1 (0.70) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL7503750 | 0.81 | MMP1 (0.42) | MMP1RAB9ANPC1CTSLCTSS | |
| SCHEMBL7506431 | 0.81 | NPC1 (0.45) | MMP1RAB9ANPC1LMNAMAPT | |
| SCHEMBL7612425 | 0.75 | MMP1 (0.56) | MMP1 | |
| SCHEMBL7612394 | 0.74 | MMP1 (0.55) | MMP1 | |
| SCHEMBL7613098 | 0.74 | MMP1 (0.85) | MMP1 | |
| SCHEMBL8458038 | 0.71 | MMP1 (0.68) | MMP1MMP3 | |
| SCHEMBL8639840 | 0.70 | NPC1 (0.40) | RAB9ANPC1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147061-A | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS; ORAL DISEASES | PFIZER INC. (US) | 2000-11-14 | — | — | US | disclosed |