SCHEMBL8156091

SCHEMBL8156091

CCCCCCc1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 9/20 0.50
GAA P10253 4/20 0.50
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
SNCA P37840 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 2/20 0.50
BCHE P06276 2/20 0.50
ACHE P22303 2/20 0.50
ALOX15 P16050 2/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8150371 1.00 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A
SCHEMBL223661 1.00 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A
SCHEMBL8147738 0.94 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL7765522 0.92 PTGS2 (0.46) SNCAACHELMNACYP3A4ADORA3
SCHEMBL29640428 0.92 PTGS2 (0.46) SNCAACHELMNACYP3A4ADORA3
SCHEMBL225844 0.92 PTGS2 (0.46) SNCAACHELMNACYP3A4ADORA3
SCHEMBL29399785 0.92 PTGS2 (0.46) SNCAACHELMNACYP3A4ADORA3
SCHEMBL8142919 0.92 PTGS2 (0.46) SNCAACHELMNACYP3A4ADORA3
SCHEMBL7528258 0.91 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A
SCHEMBL17999681 0.91 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000191643-A STABILIZATION OF ALDEHYDE PYRIDINES KOEI CHEM CO LTD 2000-07-11 JP disclosed