Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156906 | 0.95 | PIK3CD (0.45) | PIK3CDKDM4ELPAR2LPAR3 | |
| SCHEMBL8157044 | 0.89 | KDM4E (0.41) | PIK3CDKDM4ELPAR2LPAR3FAAH | |
| SCHEMBL8391424 | 0.81 | PIK3CD (0.46) | PIK3CDKDM4E | |
| SCHEMBL8158607 | 0.81 | MGLL (0.43) | PIK3CDLPAR2LPAR3FAAH | |
| SCHEMBL4874286 | 0.78 | PIK3CD (0.42) | PIK3CDKDM4E | |
| SCHEMBL8150832 | 0.77 | PIK3CD (0.45) | PIK3CDFAAH | |
| SCHEMBL8076187 | 0.76 | L3MBTL1 (0.38) | PIK3CD | |
| SCHEMBL4439323 | 0.75 | KDM4E (0.45) | PIK3CDKDM4E | |
| SCHEMBL10337440 | 0.74 | KDM4E (0.42) | PIK3CDKDM4EFAAH | |
| SCHEMBL4870336 | 0.74 | PIK3CD (0.49) | PIK3CDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086905-A | Topical compositions useful as skin penetration barriers | DISCOVERY THERAPEUTICS, INC. | 2000-07-11 | — | — | US | disclosed |