SCHEMBL8157480

SCHEMBL8157480

CCCCCCCCCCOc1cnc(-c2cc[c]cc2)nc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.53
NPC1 O15118 5/20 0.53
KDM4E B2RXH2 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
HSD17B10 Q99714 3/20 0.53
MAPT P10636 3/20 0.47
ALDH1A1 P00352 4/20 0.45
HPGD P15428 3/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NR5A1 Q13285 1/20 0.44
RARB P10826 4/20 0.43
GAA P10253 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 2/20 0.43
TSHR P16473 1/20 0.43
PLA2G4B P0C869 1/20 0.42
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447831 1.00 RAB9A (0.53) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9801755 0.88 NPC1 (0.58) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9062136 0.88 NPC1 (0.58) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9403672 0.87 RAB9A (0.47) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL6017545 0.85 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL5866494 0.85 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9318472 0.85 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9235626 0.85 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL13987904 0.85 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10
SCHEMBL9407179 0.85 NPC1 (0.71) RAB9ANPC1KDM4ESMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2174766-A None JP disclosed
JP-2174765-A None JP disclosed
EP-0806417-B1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL CO (JP) 2000-03-08 EP disclosed
US-5693251-A LIQUID CRYSTAL DISPLAYS; HIGH SPEED RESPONSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-02 US disclosed
EP-0806417-A1 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-12 EP disclosed
EP-0606090-B1 Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KK (JP) 1997-10-29 EP disclosed
US-5389293-A Light switches SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-14 US disclosed
EP-0606090-A1 Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1994-07-13 EP disclosed
JP-H02174766-A HETEROCYCLIC COMPOUND, PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT AND LIQUID CRYSTAL ELEMENT USING THE SAME SUMITOMO CHEM CO LTD 1990-07-06 JP disclosed
JP-H02174765-A OPTICALLY ACTIVE HETEROCYCLIC COMPOUND, PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT AND LIQUID CRYSTAL ELEMENT USING THE SAME SUMITOMO CHEM CO LTD 1990-07-06 JP disclosed
EP-0360622-A2 Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-28 EP disclosed