Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801755 | 1.00 | NPC1 (0.58) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9184595 | 0.91 | NPC1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9330768 | 0.91 | NPC1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8447831 | 0.88 | RAB9A (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8157480 | 0.88 | RAB9A (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL28371462 | 0.88 | RARB (0.59) | NPC1RAB9AKDM4EHSD17B10RARB | |
| SCHEMBL2877843 | 0.88 | RARB (0.59) | NPC1RAB9AKDM4EHSD17B10RARB | |
| SCHEMBL2221791 | 0.88 | RARB (0.59) | NPC1RAB9AKDM4EHSD17B10RARB | |
| SCHEMBL7731763 | 0.88 | RARB (0.59) | NPC1RAB9AKDM4EHSD17B10RARB | |
| SCHEMBL7723569 | 0.88 | RARB (0.59) | NPC1RAB9AKDM4EHSD17B10RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3263483-A | — | — | None | — | — | JP | disclosed |
| EP-0697017-A1 | NOVEL COMPOUNDS FOR USE IN LIQUID-CRYSTAL COMPOSITIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-21 | — | — | EP | disclosed |
| WO-1994026720-A1 | NOVEL COMPOUNDS FOR USE IN LIQUID-CRYSTAL COMPOSITIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-24 | — | — | WO | disclosed |
| JP-H03263483-A | LACTIC ACID DERIVATIVE AND LIQUID CRYSTAL ELEMENT USING LIQUID CRYSTAL MATERIAL CONTAINING SAME DERIVATIVE | TOSHIBA CORP | 1991-11-22 | — | — | JP | disclosed |