Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866342 | 0.84 | NPC1 (0.44) | NPC1ALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL8166048 | 0.83 | SMYD2 (0.38) | ALDH1A1SMYD2CYP3A4HTTMEN1 | |
| SCHEMBL9886817 | 0.79 | MEN1 (0.47) | ALDH1A1SMYD2CYP3A4HTTMEN1 | |
| SCHEMBL20500291 | 0.79 | MEN1 (0.47) | ALDH1A1SMYD2CYP3A4HTTMEN1 | |
| SCHEMBL7203588 | 0.79 | MEN1 (0.47) | ALDH1A1SMYD2CYP3A4HTTMEN1 | |
| SCHEMBL5426737 | 0.78 | NPC1 (0.44) | NPC1ALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL1930298 | 0.77 | NPC1 (0.43) | NPC1ALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7187471 | 0.77 | NPC1 (0.43) | NPC1ALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7782571 | 0.77 | NPC1 (0.43) | NPC1ALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL5213230 | 0.77 | NPC1 (0.43) | NPC1ALDH1A1CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110923-A | Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity | BIOCHEM PHARMA INC. (CA) | 2000-08-29 | — | — | US | disclosed |
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | disclosed |
| EP-0766683-A1 | NOVEL SUBSTITUTED PURINYL DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC (CA) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035297-A1 | NOVEL SUBSTITUTED PURINYL DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC. (CA) | 1995-12-28 | — | — | WO | disclosed |