SCHEMBL8157731

SCHEMBL8157731

C=Cc1ccccc1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.37
AKT1 P31749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036124 0.79 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL8159134 0.79 ESR1 (0.41) ALDH1A1TSHR
SCHEMBL103831 0.75 NPC1 (0.38) ALDH1A1TSHR
SCHEMBL29434633 0.73 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL5701401 0.73 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL23493448 0.73 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL373961 0.73 ALDH1A1 (0.44) ALDH1A1TSHR
Benzene SCHEMBL438681 0.72 ALDH1A1 (0.60) ALDH1A1TSHRAKT1
SCHEMBL15469236 0.70 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL2143896 0.70 ALDH1A1 (0.46) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US claimed
US-6080819-A Blends of olefin polymers and syndiotactic vinyl polymers BOREALIS AG (AT) 2000-06-27 US disclosed
EP-0884356-A2 Blends of polyolefins and syndiotactic vinyl polymeres PCD Polymere AG (AT) 1998-12-16 EP disclosed