SCHEMBL8159134

SCHEMBL8159134

C=Cc1ccccc1[Si](C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18419299 0.84 ESR1 (0.35) ESR1ESR2ALDH1A1NR1H2NR1H3
SCHEMBL15525107 0.80 LMNA (0.46) ESR1ESR2ALDH1A1TSHRNR1H2
SCHEMBL8157731 0.79 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL373961 0.79 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL12191049 0.78 ESR1 (0.54) ESR1ESR2ALDH1A1TSHRNR1H2
SCHEMBL7036124 0.76 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL23493473 0.75 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL3744488 0.75 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL15469236 0.75 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL2143896 0.75 ALDH1A1 (0.46) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0096596-B2 Microelectronic device manufacture NEC CORP (JP) 1994-03-23 EP claimed
EP-0096596-B1 MICROELECTRONIC DEVICE MANUFACTURE NEC CORPORATION (JP) 1986-06-04 EP claimed
US-4551417-A Method of forming patterns in manufacturing microelectronic devices NEC CORPORATION (JP) 1985-11-05 US claimed
EP-0096596-A1 Microelectronic device manufacture NEC CORPORATION (JP) 1983-12-21 EP claimed
WO-2000053649-A1 STYRENIC GRAFT COPOLYMER AND METHOD OF PREPARING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-09-14 WO disclosed