Cyclopentane

Cyclopentane

SCHEMBL8158405

C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.C1CCCC1.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O.CCOC=O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentane SCHEMBL28273622 1.00 ALDH1A1 (0.32) ALDH1A1MAPK1TDP1ADH1CADH1A
Cyclohexane SCHEMBL27851344 1.00 ALDH1A1 (0.32) ALDH1A1MAPK1TDP1ADH1CADH1A
Ethoxycarbonyl Group SCHEMBL27496535 1.00
Ethoxycarbonyl Group SCHEMBL27739080 1.00
Ethoxycarbonyl Group SCHEMBL27790688 0.97 ADH1C (0.30) ALDH1A1MAPK1TDP1ADH1CADH1A
Cyclohexane SCHEMBL27753019 0.97 ADH1C (0.30) ALDH1A1MAPK1TDP1ADH1CADH1A
Cyclohexane SCHEMBL27780395 0.94 SMN1; SMN2 (0.32)
Cyclohexane SCHEMBL27635324 0.92
Ethoxycarbonyl Group SCHEMBL5306888 0.90 ALDH1A1 (0.38) ALDH1A1MAPK1TDP1
Ethoxycarbonyl Group SCHEMBL1332384 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657495-B1 Halogen-free blowing agents that include cycloaliphatic hydrocarbons and are suitable for isocyanate-based polymeric foams NISSHIN SPINNING (JP) 2000-05-24 EP disclosed
EP-0657495-A1 Halogen-free blowing agents that include cycloaliphatic hydrocarbons and are suitable for isocyanate-based polymeric foams NISSHINBO INDUSTRIES, INC. (JP) 1995-06-14 EP disclosed
US-5336696-A Cycloaliphatic hydrocarbon containing 5 to 7 carbon atoms and an ether, an ester, or a ketone NISSHINBO INDUSTRIES, INC. (JP) 1994-08-09 US disclosed