Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 6/20 | 0.36 |
| ▸ | CLK1 | P49759 | 6/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 4/20 | 0.35 |
| ▸ | CLK2 | P49760 | 4/20 | 0.35 |
| ▸ | CLK3 | P49761 | 4/20 | 0.35 |
| ▸ | DYRK4 | Q9NR20 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Thiazole SCHEMBL27537468 | 0.78 | ALDH1A1 (0.86) | ALDH1A1HSD17B10DYRK1ADYRK1BDYRK2 | |
| Benzo[D]Thiazole SCHEMBL3324563 | 0.77 | ALDH1A1 (0.76) | ALDH1A1HSD17B10DYRK1ADYRK1BDYRK2 | |
| Benzo[D]Thiazole SCHEMBL10847268 | 0.76 | — | — | |
| Benzo[D]Thiazole SCHEMBL31388426 | 0.76 | — | — | |
| Benzo[D]Thiazole SCHEMBL451685 | 0.76 | — | — | |
| Benzo[D]Thiazole SCHEMBL8430 | 0.76 | — | — | |
| Benzo[D]Thiazole SCHEMBL900814 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10DYRK1ADYRK1BDYRK2 | |
| Benzo[D]Thiazole SCHEMBL27956416 | 0.76 | ALDH1A1 (0.68) | ALDH1A1HSD17B10DYRK1ADYRK1BDYRK2 | |
| Benzo[D]Thiazole SCHEMBL11715291 | 0.74 | ALDH1A1 (0.86) | ALDH1A1HSD17B10DYRK1ADYRK1BDYRK2 | |
| Benzo[D]Thiazole SCHEMBL28176141 | 0.74 | ALDH1A1 (0.86) | ALDH1A1HSD17B10DYRK1ADYRK1BDYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459093-A | Alkyl and aryl derivatives of 1-oxa-4, 9-diazaspiro undecane compounds having multimodal anti-pain activity | 埃斯蒂文博士实验室股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-6150129-A | USEFUL AS ANTIBACTERIAL AND OTHER PHARMACEUTICAL AGENTS AND AS INTERMEDIATES FOR PREPARATION OF OTHER PHARMACEUTICAL AGENTS | ISIS PHARMACEUTICALS, INC. (US) | 2000-11-21 | — | — | US | claimed |
| CN-106459093-A | Alkyl and aryl derivatives of 1-oxa-4, 9-diazaspiro undecane compounds having multimodal anti-pain activity | 埃斯蒂文博士实验室股份有限公司 | 2017-02-22 | — | — | CN | disclosed |