Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 11/20 | 0.62 |
| ▸ | RARB | P10826 | 9/20 | 0.62 |
| ▸ | RARG | P13631 | 8/20 | 0.62 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | BLVRB | P30043 | 1/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736575 | 0.86 | SSTR5 (0.50) | RARARARBRARGCYP26A1ALDH1A1 | |
| SCHEMBL8702476 | 0.82 | RARA (0.64) | RARARARBRARGCYP26A1MEN1 | |
| Terephthalic Acid SCHEMBL9872879 | 0.81 | SSTR5 (0.49) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL9141299 | 0.79 | KMT2A (0.56) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL9850145 | 0.78 | SSTR5 (0.46) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL9180357 | 0.78 | RARB (0.60) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL4420510 | 0.77 | AKR1B1 (0.43) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL9076000 | 0.77 | RARB (0.71) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL9076004 | 0.77 | RARB (0.71) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL9076001 | 0.77 | RARB (0.71) | RARARARBRARGCYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025857-A1 | RETINOIC ACID AGONISTS AS PREVENTIVE AND THERAPEUTIC AGENTS FOR NEPHRITIS | Eisai Co., Ltd. (JP) | 2000-08-09 | — | — | EP | claimed |