Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 8/20 | 0.44 |
| ▸ | RARG | P13631 | 7/20 | 0.44 |
| ▸ | RARA | P10276 | 7/20 | 0.44 |
| ▸ | RXRA | P19793 | 8/20 | 0.43 |
| ▸ | RXRB | P28702 | 6/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759232 | 0.90 | RARB (0.47) | RARBRARGRARARXRARXRB | |
| SCHEMBL9850207 | 0.89 | RARB (0.47) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL5736766 | 0.88 | CYP26B1 (0.48) | SSTR5RARBRARARXRARXRB | |
| SCHEMBL8458446 | 0.86 | RARA (0.57) | RARBRARGRARACYP3A4HSD17B10 | |
| SCHEMBL5736575 | 0.86 | SSTR5 (0.50) | SSTR5RARBRARGRARARXRA | |
| SCHEMBL9850181 | 0.85 | RXRA (0.46) | RARBRARGRARARXRARXRB | |
| SCHEMBL9850151 | 0.84 | MAPT (0.48) | RARBRARAHIF1A | |
| SCHEMBL9850206 | 0.84 | HIF1A (0.49) | RARBRARAHIF1A | |
| SCHEMBL5736859 | 0.81 | SSTR5 (0.38) | SSTR5RARBRARACYP26A1CYP26B1 | |
| Terephthalic Acid SCHEMBL9872879 | 0.81 | SSTR5 (0.49) | SSTR5RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |