SCHEMBL8159137

SCHEMBL8159137

C[Si](C)(C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CHAT P28329 2/20 0.40
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 3/20 0.39
HPGD P15428 3/20 0.39
TRPA1 O75762 2/20 0.39
RELA Q04206 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GRM5 P41594 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GRM4 Q14833 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9222035 1.00 MAOB (0.44) MAOBMEN1KMT2ACHATALDH1A1
SCHEMBL9226489 1.00 MAOB (0.44) MAOBMEN1KMT2ACHATALDH1A1
SCHEMBL13916735 0.84 CA1 (0.44) KMT2AALDH1A1KDM4EHPGDTDP1
SCHEMBL9773554 0.83 ESR1 (0.42) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL9773556 0.83 ESR1 (0.42) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL9773562 0.83 ESR1 (0.42) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL7649592 0.78 MAOB (0.50) MAOBMEN1KMT2ACHATALDH1A1
SCHEMBL5845622 0.78 MAOB (0.50) MAOBMEN1KMT2ACHATALDH1A1
SCHEMBL14946408 0.78 MAOB (0.50) MAOBMEN1KMT2ACHATALDH1A1
SCHEMBL373962 0.78 MAOB (0.50) MAOBMEN1KMT2ACHATALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0096596-B2 Microelectronic device manufacture NEC CORP (JP) 1994-03-23 EP claimed
EP-0096596-B1 MICROELECTRONIC DEVICE MANUFACTURE NEC CORPORATION (JP) 1986-06-04 EP claimed
US-4551417-A Method of forming patterns in manufacturing microelectronic devices NEC CORPORATION (JP) 1985-11-05 US claimed
EP-0096596-A1 Microelectronic device manufacture NEC CORPORATION (JP) 1983-12-21 EP claimed
CN-118002199-A Composite catalyst and preparation method and application thereof 五邑大学 2024-05-10 CN disclosed
WO-2000053649-A1 STYRENIC GRAFT COPOLYMER AND METHOD OF PREPARING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-09-14 WO disclosed
EP-0378430-A1 Novel organosilicon compound and process for producing organosilicon compound DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-07-18 EP disclosed