Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773562 | 1.00 | ESR1 (0.42) | ESR1ESR2MGAMMAPTNR1H2 | |
| SCHEMBL9773556 | 1.00 | ESR1 (0.42) | ESR1ESR2MGAMMAPTNR1H2 | |
| SCHEMBL7898054 | 0.87 | MAPT (0.38) | ESR1ESR2MGAMMAPTNR1H2 | |
| SCHEMBL7898055 | 0.87 | MAPT (0.38) | ESR1ESR2MGAMMAPTNR1H2 | |
| SCHEMBL5779325 | 0.85 | ESR1 (0.37) | ESR1ESR2MGAMMAPTNR1H2 | |
| SCHEMBL9222035 | 0.83 | MAOB (0.44) | LMNATSHRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8159137 | 0.83 | MAOB (0.44) | LMNATSHRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9226489 | 0.83 | MAOB (0.44) | LMNATSHRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28721082 | 0.81 | ALDH1A1 (0.41) | ESR1ESR2MGAMMAPTLMNA | |
| SCHEMBL940804 | 0.80 | MAPT (0.45) | ESR1ESR2MGAMMAPTNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068381-A | Reaction of silane with acetylene compound for use as a crosslinking agent and as a photosensitive agent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-11-26 | — | — | US | disclosed |