Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL8159324 | 1.00 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL2281229 | 0.94 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL2281231 | 0.94 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL3231 | 0.94 | — | — | |
| Aspartic Acid SCHEMBL1526976 | 0.94 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL11065189 | 0.94 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL996424 | 0.94 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| D-Aspartate SCHEMBL145539 | 0.94 | — | — | |
| Aspartic Acid SCHEMBL3230 | 0.94 | — | — | |
| Aspartic Acid SCHEMBL11065185 | 0.94 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572565-A | Asparagus polyurea quick-fixing glue | 王建华 | 2023-01-06 | — | — | CN | claimed |
| CN-109511493-A | Sowing planting method is robbed in Wheat after rice extension in Henan south | 信阳市农业科学院 | 2019-03-26 | — | — | CN | claimed |
| CN-109511492-A | Henan south Wheat after rice wetland robs sowing planting method | 信阳市农业科学院 | 2019-03-26 | — | — | CN | claimed |
| CN-105482117-A | Polyaspartic acid/urea graft copolymer as well as preparation method and application thereof | BEIJING INST TECHNOLOGY | 2016-04-13 | — | — | CN | claimed |
| CN-202007198-U | Polyaspartic acid urea production line | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2011-10-12 | — | — | CN | claimed |
| WO-2000035998-B1 | ASSOCIATION OF COMPOUNDS IN CARBON DIOXIDE AND THE GELS AND/OR FOAMS FORMED THEREFROM | UNIV YALE (US) | 2000-11-16 | — | — | WO | claimed |
| WO-2000035998-A2 | ASSOCIATION OF COMPOUNDS IN CARBON DIOXIDE AND THE GELS AND/OR FOAMS FORMED THEREFROM | YALE UNIVERSITY (US) | 2000-06-22 | — | — | WO | claimed |
| CN-111635519-A | Synthetic method and application of water-based aspartic acid resin | 深圳市前海博扬研究院有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-105482117-A | Polyaspartic acid/urea graft copolymer as well as preparation method and application thereof | BEIJING INST TECHNOLOGY | 2016-04-13 | — | — | CN | disclosed |
| CN-102267921-B | A kind of synthesis oxamide continuous processing | CHEN YIDUN (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103145508-B | A kind of poly-sky enzymuria element and production method thereof and application | Shijiazhuang Zhongnong Xingtai Biotechnology Co., Ltd. (CN) | 2016-02-03 | — | — | CN | disclosed |
| EP-2792354-A2 | COMPOSITION OF PROTECTORS OF ACUTE AND CHRONIC HEPATIC ENCEPHALOPATHY AND METHOD FOR TREATING ACUTE AND CHRONIC HEPATIC ENCEPHALOPATHY | Obshchestvo S Ogranichennoj Otvetstvennostju «Biotekhnologii Pyshchino» (RU) | 2014-10-22 | — | — | EP | disclosed |
| CN-104045468-A | Special functional urea formaldehyde fertilizer for garlic and preparation method thereof | SHANDONG SHIBEIMEI FERTILIZER DEV CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-103145508-A | Aspartate urea and production method and application thereof | SHIJIAZHUANG ZHONGNONG XINGTAI BIOTECHNOLOGY CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-102910967-A | Special urea formaldehyde efficacy-improved fertilizer for garlic and preparation method of fertilizer | SHANDONG SHIBEIMEI FERTILIZER DEV CO LTD | 2013-02-06 | — | — | CN | disclosed |
| CN-101747103-B | Dedicated fertilizer for producing green nanguo pear and preparation and application method thereof | INST APPLIED ECOLOGY CAS | 2012-09-26 | — | — | CN | disclosed |
| CN-102267921-A | Continuous processing technology for synthesis of oxamide | — | 2011-12-07 | — | — | CN | disclosed |
| CN-202007198-U | Polyaspartic acid urea production line | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2011-10-12 | — | — | CN | disclosed |
| CN-101747103-A | Dedicated fertilizer for producing green nanguo pear and preparation and application method thereof | INST APPLIED ECOLOGY CHINA | 2010-06-23 | — | — | CN | disclosed |
| WO-2000035998-A2 | ASSOCIATION OF COMPOUNDS IN CARBON DIOXIDE AND THE GELS AND/OR FOAMS FORMED THEREFROM | YALE UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |