SCHEMBL8159332

SCHEMBL8159332

Cc1c([Zr]([SiH3])(c2ccccc2)(c2ccccc2)c2ccc3c(c2C)Cc2ccccc2-3)ccc2c1Cc1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.40
PNMT P11086 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
KDR P35968 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
SRD5A2 P31213 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
PDGFRB P09619 1/20 0.31
METAP2 P50579 1/20 0.31
HTR2B P41595 2/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8155761 0.99 PGR (0.39) PGRPNMTNPC1RAB9ACA1
SCHEMBL6557454 0.81 PNMT (0.44) PGRPNMTNPC1RAB9ACA1
Hydrochloric Acid SCHEMBL6558701 0.80 PNMT (0.42) PGRPNMTNPC1RAB9ACA1
Hydrochloric Acid SCHEMBL6558644 0.76 PGR (0.42) PGRPNMTNPC1RAB9ACA1
SCHEMBL8679358 0.73 PGR (0.40) PGRPNMTNPC1RAB9ACA1
SCHEMBL358531 0.73 PNMT (0.47) PGRPNMTNPC1RAB9ACA1
SCHEMBL29413832 0.73 PNMT (0.47) PGRPNMTNPC1RAB9ACA1
SCHEMBL7641535 0.73 PNMT (0.43) PGRPNMTNPC1RAB9ACA1
Hydrochloric Acid SCHEMBL7577443 0.72 PGR (0.39) PGRPNMTNPC1RAB9ACA1
Fluorene SCHEMBL28414270 0.72 PNMT (0.46) PGRPNMTNPC1RAB9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628565-B1 Bis fluorenyl metallocenes and use thereof PHILLIPS PETROLEUM CO (US) 2000-04-26 EP claimed