Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194662 | 1.00 | AR (0.52) | ARMAOBNR1H4ALOX5TUBB1 | |
| SCHEMBL7194657 | 1.00 | AR (0.52) | ARMAOBNR1H4ALOX5TUBB1 | |
| SCHEMBL4849390 | 0.86 | ALDH1A1 (0.52) | ARMAOBNR1H4ALOX5TUBB1 | |
| SCHEMBL7192651 | 0.82 | MAPT (0.57) | ALOX5CYP1A1CYP1B1CYP1A2TNFRSF1A | |
| SCHEMBL7192645 | 0.82 | MAPT (0.57) | ALOX5CYP1A1CYP1B1CYP1A2TNFRSF1A | |
| SCHEMBL7196488 | 0.80 | TUBB1 (0.64) | ARMAOBNR1H4TUBB1CYP1A1 | |
| SCHEMBL31338657 | 0.80 | TUBB1 (0.64) | ARMAOBNR1H4TUBB1CYP1A1 | |
| SCHEMBL31436373 | 0.80 | CHRNA7 (0.60) | ARMAOBNR1H4TUBB1CYP1A1 | |
| SCHEMBL7196491 | 0.80 | TUBB1 (0.64) | ARMAOBNR1H4TUBB1CYP1A1 | |
| SCHEMBL31436353 | 0.80 | CHRNA7 (0.60) | ARMAOBNR1H4TUBB1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | disclosed |