SCHEMBL8159477

SCHEMBL8159477

COC(=O)c1ccccc1CS(=O)(=O)NC(=O)ONc1nc(OC)cc(OC)n1

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
LMNA P02545 1/20 0.40
RORC P51449 1/20 0.39
TSHR P16473 1/20 0.38
GAA P10253 1/20 0.38
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
ADCY10 Q96PN6 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bensulfuron Methyl SCHEMBL55028 0.85 GAA (0.51) ALDH1A1SMN1; SMN2MAPTTP53GLA
Bensulfuron Methyl SCHEMBL29368260 0.85 GAA (0.51) ALDH1A1SMN1; SMN2MAPTTP53GLA
Bensulfuron Methyl SCHEMBL6382944 0.85 GAA (0.51) ALDH1A1SMN1; SMN2MAPTTP53GLA
Bensulfuron Methyl SCHEMBL27491070 0.85 GAA (0.51) ALDH1A1SMN1; SMN2MAPTTP53GLA
SCHEMBL1765911 0.85 MAPT (0.47) ALDH1A1SMN1; SMN2MAPTTP53GLA
Bensulfuron Methyl SCHEMBL15524972 0.84 GAA (0.50) ALDH1A1SMN1; SMN2MAPTTP53GLA
SCHEMBL10524876 0.84 MAPT (0.48) ALDH1A1SMN1; SMN2MAPTTP53GLA
SCHEMBL10394921 0.83 MAPT (0.51) ALDH1A1SMN1; SMN2MAPTTP53GLA
SCHEMBL9461802 0.83 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPTTP53GLA
SCHEMBL9835967 0.82 MAPT (0.46) ALDH1A1SMN1; SMN2MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0666708-B1 HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES FMC CORP (US) 2000-10-04 EP disclosed
EP-0666708-A4 HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES. 1995-08-23 EP disclosed
EP-0666708-A1 HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES FMC CORPORATION (US) 1995-08-16 EP disclosed
WO-1994009629-A1 HERBICIDAL COMPOSITIONS CONTAINING TRIAZOLINONES FMC CORPORATION (US) 1994-05-11 WO disclosed
US-5208212-A Synergistic FMC CORPORATION (US) 1993-05-04 US disclosed