Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152892 | 0.90 | TDP1 (0.45) | KMT2AMEN1LMNAALDH1A1NR1H4 | |
| SCHEMBL8160297 | 0.89 | TSHR (0.47) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8154501 | 0.88 | TSHR (0.48) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27975595 | 0.85 | LMNA (0.57) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8160067 | 0.84 | KMT2A (0.43) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11430344 | 0.80 | MEN1 (0.56) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11430341 | 0.80 | MEN1 (0.56) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11419215 | 0.78 | MEN1 (0.66) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11419211 | 0.78 | MEN1 (0.66) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9204754 | 0.77 | LMNA (0.44) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | claimed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | claimed |