Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203802 | 0.92 | BCHE (0.41) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9203895 | 0.89 | MEN1 (0.51) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL27975595 | 0.87 | LMNA (0.57) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9206588 | 0.85 | CYP11B1 (0.34) | KMT2AALDH1A1HPGDSMN1; SMN2CYP2D6 | |
| SCHEMBL9202752 | 0.84 | HDAC8 (0.39) | LMNAALDH1A1HPGDSMN1; SMN2KIF11 | |
| SCHEMBL9208251 | 0.82 | PRSS1 (0.33) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9207327 | 0.82 | ALDH1A1 (0.45) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9200646 | 0.80 | ELANE (0.39) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9204169 | 0.78 | ALDH1A1 (0.41) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9202154 | 0.78 | ALDH1A1 (0.41) | LMNAKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |