Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053653 | 0.74 | NOS3 (0.38) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL4445615 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL8161883 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8164982 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL10603904 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL81441 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL8421241 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL650348 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL8464590 | 0.68 | — | — | |
| SCHEMBL6358801 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084043-A | BRIDGED FUSED CYCLOPENTADIENE RINGS SUCH AS HEXAHYDROAZULENE WITH GIVEN SUBSTITUENTS DERIVATIVES WITH A GROUP 4B TRANSITION METAL; PRODUCES ALPHA-OLEFIN POLYMERS HAVING HIGH MELTING POINT AND HIGH MOLECULAR WEIGHT IN A HIGH YIELD | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0697418-B1 | Catalyst component for polymerization of alpha-olefins and process for producing alpha-olefin polymers using the same | MITSUBISHI CHEM CORP (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0697418-A1 | Catalyst component for polymerization of alpha-olefins and process for producing alpha-olefin polymers using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-02-21 | — | — | EP | disclosed |